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Beilstein J. Org. Chem. 2016, 12, 1428–1433, doi:10.3762/bjoc.12.137
Graphical Abstract
Figure 1: BHL and OdDHL are two natural AHL-based signaling molecules used by P. aeruginosain quorum sensing....
Scheme 1: Unexpected synthesis of compound 4. The synthesis of 2 was achieved by a previously reported route [9]....
Figure 2: a) Inhibitory effect of compound 4 (200 μM suspension in DMSO) on pyocyanin production in PAO1. DMS...
Figure 3: Binding poses of OdDHL and compound 4 in OdDHL binding site. Hydrogen bonds are shown in black dott...